Fatal Hyperammonemic Brain Injury from Valproic Acid Exposure
نویسندگان
چکیده
منابع مشابه
Fatal Hyperammonemic Brain Injury from Valproic Acid Exposure
BACKGROUND Hyperammonemia is known to cause neuronal injury, and can result from valproic acid exposure. Prompt reduction of elevated ammonia levels may prevent permanent neurological injury. We report a case of fatal hyperammonemic brain injury in a woman exposed to valproic acid. CASE A 38-year-old woman with schizoaffective disorder and recent increase in valproic acid dosage presented wit...
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BACKGROUND A patient with an early diagnosed epilepsy Valproic acid is one of the most widely used antiepileptic drugs. Hyperammonemic encephalopathy is a rare, but potentially fatal, adverse drug reaction to valproic acid. CASE DESCRIPTION A patient with an early diagnosed epilepsy, treated with valproic acid, experienced an altered mental state after 10 days of treatment. Valproic acid seru...
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Valproic acid-induced hyperammonemic encephalopathy is a rare yet serious adverse drug reaction. Medication interactions such a valproic acid and topiramate can precipitate an event. We present the case of a 52-year-old female that presented with acute mental status change and hypersomnolence due to hyperammonemia caused by a valproic acid derivative. The patient improved after withdrawal of th...
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ژورنال
عنوان ژورنال: Case Reports in Neurology
سال: 2012
ISSN: 1662-680X
DOI: 10.1159/000345226